Coenzyme Q10 has the dual identity of medicine and health care products, and has become hot in recent years due to the overwhelming publicity of businesses. In the promotion of health products, coenzyme Q10 has many functions such as protecting the heart, lowering blood pressure and lipid, anti-aging, anti-cancer, and improving human immunity, attracting more and more patients and their families to consult how to use it.Does CoQ10 really have so many magical effects? Today, let’s take a look at the function of coenzyme Q10, the applicable population and the precautions for taking it.
What is CoQ10
Coenzyme Q10, also known as ubiquitin ketone, is ubiquitous in animals and most bacteria and belongs to a family of coenzymes. Generally contains 6-10 isoprene units of the side chain, mammals contain 10, so it is called coQ10.It was first discovered in 1957 by Professor Frederick Crane of the University of Wisconsin in the mitochondria of bovine heart cells.Coenzyme Q10 is fat-soluble, similar to vitamin, which can be synthesized by the body itself, mainly involved in aerobic cell respiration, plays an important role in proton transfer and electron transfer in the human respiratory chain, and can be used as an activator of cell metabolism and cell respiration, as well as an important antioxidant and non-specific immune booster, which can promote oxidative phosphorylation and protect the structural integrity of biofilm.The concentration and content of coenzyme Q10 are also relatively high in organs with high energy requirements such as the heart, liver, kidney and pancreas. Coq10 is most distributed in mitochondria (45%-50%) and least distributed in cytoplasm (5%-10%).
What are the effects of coenzyme Q10?
The FDA has not approved CoQ10 as a drug, and in the United States, CoQ10 is marketed as a food supplement.In China, coenzyme Q10 is not only a drug approved by the State Food and Drug Administration (CFDA), but also the main or additive ingredient of many health products.Consult the related drugs of coenzyme Q10, the oral dosage form (tablet, capsule) and injection dosage form are currently approved for market.Indications approved by the oral dosage form specification are:
This product is used for the adjuvant treatment of the following diseases:
1. Cardiovascular diseases, such as viral myocarditis and chronic cardiac insufficiency.
2. Hepatitis, such as: viral hepatitis, subacute liver necrosis, chronic active hepatitis.
3. Comprehensive treatment of cancer: it can alleviate some adverse reactions caused by radiotherapy and chemotherapy.
About three-quarters of CoQ10 in the human body is produced by itself, and only a small part comes from food supplements. Coenzyme Q10 is found in Marine fish, beef, chicken, nuts, seeds and other foods.However, coQ10 is produced in the mitochondria and mainly exists in the mitochondrial biofilm, so it is difficult for exogenous coQ10 to really enter the mitochondrial biofilm from the outside and achieve its role.For most of the general population, the amount of coenzyme Q10 synthesized by itself is large enough that there will be no shortage of problems, therefore, it is not recommended that healthy people use drug coenzyme Q10 supplement.
So, based on the functional orientation of the drug, which patients can use coQ10?According to the drug instructions approved by CFDA, it can be used for patients who meet the drug indications, such as: patients with viral myocarditis, chronic heart dysfunction, congestive heart failure, coronary heart disease, hypertension, arrhythmia and other cardiovascular diseases; Patients with viral hepatitis, subacute liver necrosis, chronic active hepatitis; Cancer patients receiving radiotherapy or chemotherapy; Patients with secondary aldosteronism; Cervical traumatic sequelae patients; Patients with cerebrovascular disorders; Patients with hemorrhagic shock.However, it must be noted that coenzyme Q10 is an adjuvant therapy, and in the treatment of the above diseases, the main therapeutic drugs recommended by the relevant disease guidelines must be the main treatment, and the combined use of coenzyme
Precautions for use
1.Coenzyme Q10 is a fat-soluble drug, it is recommended to take orally after meals, can improve bioavailability and reduce the incidence of stomach upset.
2. The safety of coenzyme Q10 in children, the elderly, pregnant and nursing patients is not clear.
3. Coenzyme Q10 intravenous preparation can cause anaphylactic shock. The patient should be asked about the history of drug allergy before medication, and should be closely monitored during medication. If symptoms and signs such as rash, itching, dyspnea, and decreased blood pressure appear, the medication should be stopped immediately and treated in time.
4. Coenzyme Q10 intravenous preparation is easy to decompose by light. Precautions against light should be taken during intravenous infusion.
As a professional Coenzyme Q10 manufacturer, we have the following selling points to attract customers: Premium Product Quality: We are committed to providing customers with premium Coenzyme Q10 products, and all products undergo strict quality control and testing to ensure compliance with international standards and specifications. We use advanced production technology and equipment to ensure the purity, stability and efficiency of our products. International Certification and Recognition: Our Coenzyme Q10 products have been certified by multiple international certification agencies, such as ISO 9001 and GMP certification, etc. If you have any questions please contact us now.
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Post time: Oct-30-2023
